A graduate student position is available at the Department of Clinical Tumor Biology, University Hospital Tübingen, to study molecular pathways that control cancer progression. The aim of the project is to identify critical mechanisms that regulate the function of oncoproteins and tumor supressors and allow the development of effective strategies for cancer therapy. The project will focus on the role of ubiquitin system - an extensive network of protein-modifying enzymes that regulate most of the cellular proteins and provide an excellent resource of potential drug targets.
Activities and responsibilities
The sucessful candidate will use state-of-the-art technologies, including sgRNA library screening, transcriptome and proteome analysis by next-generation sequencing and mass spectrometry as well as realistic models of human cancer. The project involves collaborations with expert groups in structural biology, molecular modelling and medicinal chemistry to design and develop experimental compounds targeting the identified mechanisms.
To apply, please send a personal cover letter, the CV with details of your research experience and copies of the MSc diploma with transcripts to Prof. Nikita Popov (firstname.lastname@example.org).
The department hosts an international team of scientists and medical doctors and will provide access to training in many areas of tumor biology, lectures by world-leading scientists and technology seminars. The salary is at 65% TVL E13 with the initial contract for three years.
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