Postdoctoral Researcher - Tau-Mediated Neurodegeneration in Alzheimer’s Disease (AD) (m/f)

 BioMed X GmbH  Heidelberg

2 Postdoctoral Researchers (m/f)


BioMed X Innovation Center, Im Neuenheimer Feld 583, 69120 Heidelberg, Germany

About BioMed X

The BioMed X Innovation Center is an exciting new collaboration model at the interface between academia and industry. At our center, distinguished early career scientists recruited from all over the world are working jointly on novel pre-clinical research projects in the fields of biomedicine, molecular biology, cell biology, diagnostics and bioinformatics. These interdisciplinary project teams are conducting groundbreaking biomedical research in an open innovation lab facility on the campus of the University of Heidelberg, under the guidance of experienced mentors from academia and industry while expanding their scientific network and receiving an intensive entrepreneurship and leadership training.
Each BioMed X project team is sponsored by an industry partner. The sponsor of this call for application is AbbVie.

What we are looking for

Applications are welcome from early career scientists with an outstanding track record in the field of:
Tau-Mediated Neurodegeneration in Alzheimer’s Disease (AD)
The goal is the identification of novel ways to address tau pathology for the treatment of AD beyond anti-tau antibodies. Recent findings demonstrate that the intracellular pathological tau molecules become self-propagating, a process which is also thought to play a role in disease progression. Not surprisingly then, tau-mediated pathology may be addressed by targeting this process and the underlying mechanistic components. We are particularly interested in proposals focusing on intracellular tau processing and clearance, including proteostasis, as well as studies to elucidate how tau processing is affected by AD-related alterations such as elevated oligomeric amyloid-beta, or the genetic factors linked to late onset AD. Proposals building on very original ideas supported by first experimental findings are particularly encouraged.
Candidates for postdoctoral positions are expected to have several years of research experience and a certain degree of specialization in one or more relevant cutting-edge technologies.

What we offer

The posts are offered for a period of two to four years with an option for a permanent position.
As part of the research group in the above mentioned field the posts include a generous funding package covering personal salary, consumables, services, travels, as well as access to the core facilities of neighboring research institutions and biotechnology companies in Heidelberg.
There is flexibility over starting dates, but successful applicants are welcome to take up post starting September 1, 2015.

Application & Selection Process

Applications are to be made online at
Only applications received before May 10, 2015 will be considered. As part of the online application procedure candidates will be required to enter detailed information about their previous work and submit a competitive project proposal.
After a first selection round, candidates will be invited to a five-day innovation boot camp in Heidelberg. The invitation includes full coverage of travel expenses, accommodation, sightseeing, and food for the entire workshop which will take place from July 11 to 15, 2015. With guidance of experienced mentors, candidates will jointly work on their project
proposals and present them in front of a jury on the final day. Successful candidates will be
offered a position at the BioMed X Innovation Center.


BioMed X Innovation Center
Im Neuenheimer Feld 583
69120 Heidelberg
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